Uridine diphosphate glucose

SKU: orb1706057

Description

Uridine diphosphate glucose (UDP-glucose) is a crucial nucleotide sugar that acts as a glucose donor in the biosynthesis of glycogen, glycoproteins, and glycolipids. It is widely used in research on carbohydrate metabolism and serves as an agonist for the P2Y14 receptor in both in vitro and in vivo studies.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 133-89-1
• MW: 566.3
• Purity: 99.75% (May vary between batches)
• Formula: C₁₅H₂₄N₂O₁₇P₂
• SMILES: O[C@H]1[C@@H](O[C@H](COP(OP(O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)(=O)O)(=O)O)[C@H]1O)N3C(=O)NC(=O)C=C3
• Target: Endogenous Metabolite,P2Y Receptor

Bioactivity

• In Vitro:
  Method: Neutrophils were treated with varying concentrations (0–100 μM) of Uridine diphosphate glucose and incubated for 24 hours. In some groups, PPTN was co-administered. Cell viability and apoptosis were then assessed. Result: Uridine diphosphate glucose treatment decreased neutrophil viability and increased apoptosis, effects that were attenuated by the addition of PPTN.

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Human Endogenous Metabolite, UDP-D-Glucose, Uridine 5′-diphosphoglucose, Uridine diphosphate glucose

Compound Identifiers

PubChem CID

8629