Ureidopropionic acid

• Catalog Number: orb1302450
• Category: Small Molecules
• Description: Ureidopropionic acid
• Purity: ≥98%
• MW: 132.12
• Biological Activity: Ureidopropionic acid (3-Ureidopropionic acid) is an intermediate in the metabolism of uracil. More specifically it is a breakdown product of dihydrouracil and is produced by the enzyme dihydropyrimidase. It is further decomposed to beta-alanine via the enzyme beta-ureidopropionase. Ureidopropionic acid is essentially a urea derivative of beta-alanine. High levels of Ureidopropionic acid are found in individuals with beta-ureidopropionase (UP) deficiency. Enzyme deficiencies in pyrimidine metabolism are associated with a risk for severe toxicity against the antineoplastic agent 5-fluorouracil.
• CAS Number: 462-88-4
• Formula: C₄H₈N₂O₃
• SMILES: NC(=O)NCCC(O)=O
• Storage: -20°C
• Note: For research use only