Urapidil hydrochloride

SKU: orb1310950

Description

Urapidil HCl is a dual-acting agent that functions as a serotonin 5-HT1A receptor agonist and an α1-adrenoceptor antagonist. It is utilized in research to investigate mechanisms of vasodilation and hypertension in both in vitro receptor binding assays and in vivo animal models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 64887-14-5
• MW: 423.94
• Purity: 99.93% (May vary between batches)
• Formula: C₂₀H₂₉N₅O₃·HCl
• SMILES: Cl.COC1=CC=CC=C1N1CCN(CCCNC2=CC(=O)N(C)C(=O)N2C)CC1
• Target: Adrenergic Receptor,5-HT Receptor
• Solubility: DMSO:8.33 mg/mL (19.65 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.36 mM);H2O:200.5 mM

Bioactivity

• Target IC50:
  5-HT1A receptor:6.4 (pIC50)|α2-adrenoceptor:4.38 (pIC50)|α1-adrenoceptor:6.13 (pIC50)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Serotonin Receptor, α-adrenergic receptor, Urapidil, Urapidil HCl, Urapidil Hydrochloride, Urapidil hydrochloride, Inhibitor, inhibit, antihypertensive effect, 5-hydroxytryptamine Receptor, 5HTReceptor, 5-HT, 5HT Receptor, Adrenergic Receptor, AdrenergicReceptor, 5-HT Receptor, Beta Receptor

Compound Identifiers

PubChem CID

167980