Uprifosbuvir

SKU: orb1699048

Description

Uprifosbuvir (MK-3682) is a prodrug of a uridine monophosphate analog that potently inhibits the HCV NS5B RNA polymerase. It has demonstrated significant antiviral activity in both in vitro assays and in vivo animal models for the study of chronic hepatitis C virus infection and antiviral mechanisms.

Research Area

Infectious Disease & Virology, Protein Biochemistry

Key Properties

• CAS Number: 1496551-77-9
• MW: 545.91
• Purity: >99.99% (May vary between batches)
• Formula: C₂₂H₂₉ClN₃O₉P
• SMILES: C[C@]1(Cl)[C@@H](O[C@H](COP(OC2=CC=CC=C2)(N[C@@H](C(OC(C)C)=O)C)=O)[C@H]1O)N3C(=O)NC(=O)C=C3
• Target: HCV Protease

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

IDX 21437, IDX21437, IDX-21437, HCV Protease, HCVProtease, HCV, MK 3682, MK3682, MK-3682, Uprifosbuvir

Compound Identifiers

PubChem CID

90055896