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Catalog Number | orb1685483 |
---|---|
Category | Small Molecules |
Description | Upadacitinib tartrate |
CAS Number | 1607431-21-9 |
Purity | 98% |
MW | 602.521 |
SMILES | O.O.O.O.O[C@H]([C@@H](O)C(O)=O)C(O)=O.CC[C@@H]1CN(C[C@@H]1c1cnc2cnc3[nH]ccc3n12)C(=O)NCC(F)(F)F |
Formula | C21H33F3N6O11 |
Biological Activity | Upadacitinib is a potent and selective JAK inhibitor. Upadacitinib is approximately 74 fold selective for Jak1 over Jak2 in cellular assays dependent on specific, relevant cytokines. Upadacitinib demonstrates efficacy in rat arthritis models. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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