Unesbulin

SKU: orb1309210

Description

Unesbulin (PTC596) is an orally bioavailable small molecule that selectively inhibits the BMI-1 protein. This compound is utilized in preclinical research, including in vitro cell studies and in vivo models, to investigate pathways involved in oncology and stem cell biology.

Research Area

Cell Biology, Molecular Biology

Key Properties

• CAS Number: 1610964-64-1
• MW: 420.34
• Purity: 100.00% (May vary between batches)
• Formula: C₁₉H₁₃F₅N₆
• SMILES: Cc1nc2ccc(F)cc2n1-c1nc(N)c(F)c(Nc2ccc(cc2)C(F)(F)F)n1
• Target: BMI-1|||Apoptosis
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.38 mM);DMSO:3.67 mg/mL (8.73 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

AML, APC/CCDC20, Apoptosis, BMI1, BMI-1, integration, Inhibitor, leukemia, leukemic, G2/M, inhibit, murine, p53, Moloney, orally, PTC 596, PTC596, PTC-596, Unesbulin, virus

Compound Identifiers

PubChem CID

74223469