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UNC9994 hydrochloride

SKU: orb1687190

Description

UNC9994 hydrochloride is a β-arrestin-biased agonist of the dopamine D2 receptor (D2R) with a Ki of 79 nM. It acts as a Gi-regulated antagonist of cAMP production while potently stimulating D2R/β-arrestin-2 signaling, leading to observed psychostimulatory effects in research models. This profile makes it a valuable tool for studying biased signaling in neuropharmacology, particularly in psychiatric and neurological disorders.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2108826-33-9
MW457.84
FormulaC21H23Cl3N2OS
SMILESCl.Clc1cccc(C2CCN(CCCOc3ccc4scnc4c3)CC2)c1Cl
Target5-HT Receptor,Dopamine Receptor,Others,Arrestin

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

UNC9994 hydrochloride (orb1687190)

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