UNC8969

SKU: orb2814725

Description

UNC8969 is a potent and selective macrocyclic dual inhibitor of MERTK and AXL with low nanomolar IC50 values. It demonstrates favorable pharmacokinetics and has shown significant anti-tumor efficacy in cellular models of lung cancer, supporting its utility in oncology research for studying TAM receptor signaling in vitro and in vivo.

Research Area

Signal Transduction

Key Properties

• CAS Number: 3036049-17-6
• MW: 535.68
• Formula: C₂₉H₄₁N₇O₃
• SMILES: CC1=CC=C(N2)C=C1OC/C=C\CNC3=NC2=C(C(N[C@@H]4CC[C@@H](C(NCCN(CC)CC)=O)CC4)=O)C=N3
• Target: TAM Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171391782