UNC4976 TFA

SKU: orb1983370

Description

UNC4976 TFA is a peptidomimetic CBX7 chromodomain positive allosteric modulator (PAM). It functions by disrupting the specific recruitment of CBX7 to H3K27me3-marked genes while promoting its non-specific binding to DNA and RNA. This compound is a valuable chemical probe for studying Polycomb repressive complex 1 (PRC1) function in epigenetic regulation, applicable in both in vitro binding assays and cellular models.

Research Area

Epigenetics & Chromatin, Immunology & Inflammation

Key Properties

• Target: Histone Methyltransferase
• MW: 961.12
• Formula: C₄₉H₇₁F₃N₆O₁₀

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Histone Methyltransferase