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UNC4976 TFA

SKU: orb1983370

Description

UNC4976 TFA is a peptidomimetic CBX7 chromodomain positive allosteric modulator (PAM). It functions by disrupting the specific recruitment of CBX7 to H3K27me3-marked genes while promoting its non-specific binding to DNA and RNA. This compound is a valuable chemical probe for studying Polycomb repressive complex 1 (PRC1) function in epigenetic regulation, applicable in both in vitro binding assays and cellular models.

Research Area

Epigenetics & Chromatin

Images & Validation

Key Properties

TargetHistone Methyltransferase
Molecular Weight961.12

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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UNC4976 TFA (orb1983370)

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