UNC 569 hydrochloride

SKU: orb1306407

Description

UNC 569 hydrochloride is a potent, ATP-competitive inhibitor of Mer (IC50=2.9 nM; Ki=4.3 nM), with additional activity against Axl and Tyro3. It is a valuable research tool for studying the role of TAM kinases in cancers such as acute lymphoblastic leukemia and atypical teratoid/rhabdoid tumors in experimental models.

Research Area

Signal Transduction

Key Properties

• Target: TAM Receptor,TAM Receptor
• Molecular Weight: 432.96
• Purity: >99.99% (May vary between batches)
• Formula: C₂₂H₃₀ClFN₆
• SMILES: CCCCNC1=NC=C(C2=N1)C(C3=CC=C(F)C=C3)=NN2C[C@@H]4CC[C@@H](N)CC4.Cl

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

1350547-65-7, 1350547-65-7 Free base, AXL, Mer, TAMReceptor, TAM Receptor, Tyro3, UNC 569 hydrochloride, UNC 569 Hydrochloride, UNC 569 hydrochloride (1350547-65-7 Free base), UNC-569 Hydrochloride, UNC569 Hydrochloride

Compound Identifiers

PubChem CID

168012328