Umbralisib sulfate

SKU: orb1744846

Description

Umbralisib sulfate is an orally bioavailable, dual inhibitor of PI3Kδ (EC50=22.2 nM) and CK1ε. It exhibits distinct immunomodulatory activity and is utilized in preclinical research for hematological malignancies, including studies on CLL cell lines and in vivo models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1532533-75-7
• MW: 669.63
• Formula: C₃₁H₂₆F₃N₅O₇S
• SMILES: S(=O)(=O)(O)O.NC1=C2C(=NN([C@@H](C)C3=C(C(=O)C=4C(O3)=CC=C(F)C4)C5=CC(F)=CC=C5)C2=NC=N1)C6=CC(F)=C(OC(C)C)C=C6
• Target: Others,Casein Kinase,PI3K

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

86707829