UM4118

SKU: orb2308712

Description

UM4118 (N-quinolin-8-ylpyridine-2-carboxamide) is a copper ionophore that induces cuproptosis, a unique copper-dependent mitochondrial cell death pathway. It serves as a research tool for studying acute myeloid leukemia, with in vitro studies showing it does not inhibit VEGF or b-FGF stimulated endothelial cell proliferation at low micromolar concentrations.

Research Area

Cell Biology

Key Properties

• CAS Number: 324530-92-9
• MW: 249.27
• Purity: 99.93% (May vary between batches)
• Formula: C₁₅H₁₁N₃O
• SMILES: O=C(NC1=CC=CC2=CC=CN=C21)C3=NC=CC=C3
• Target: Cuproptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

N-quinolin-8-ylpyridine-2-carboxamide, Cuproptosis, UM4118

Compound Identifiers

PubChem CID

12090074