UK140

SKU: orb2942784

Description

UK140 is a selective urokinase-type plasminogen activator (uPA) inhibitor, exhibiting a Ki of 0.20 µM for human uPA and 2.79 µM for mouse uPA. It is a valuable research tool for investigating uPA's role in cancer cell invasion and metastasis, applicable in both in vitro enzymatic assays and in vivo tumor models.

Research Area

Metabolism Research

Key Properties

• Target: PAI-1
• MW: 1732.91
• Formula: C₇₂H₁₀₅N₁₉O₂₅S₃
• SMILES: C[C@@H](C(=O)N[C@H]1CSCC2=CC3=CC(=C2)CSC[C@@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N4CCC[C@H]4C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSC3)C(=O)NCC(=O)O)CO)CO)CC(=O)O)C(C)C)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CC(=O)N)CO)CCCCN)CC5=CC=CC=C5)CO)N

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172677251