UK-122 TFA salt

SKU: orb1986839

Description

UK-122 is a potent and selective urokinase-type plasminogen activator (uPA) inhibitor with a Ki of 20 nM and a cell-free IC50 of 0.2 µM. It exhibits minimal cytotoxicity (IC50 >100 µM) but significantly impedes the migration and invasion of pancreatic CFPAC-1 cancer cells in vitro, supporting its use in metastasis research.

Research Area

Immunology & Inflammation, Metabolism Research

Key Properties

• CAS Number: 1186653-73-5
• MW: 405.33
• Formula: C₁₉H₁₄F₃N₃O₄
• SMILES: C(C(O)=O)(F)(F)F.C(=C\1/N=C(OC1=O)C2=CC=CC=C2)\C3=CC=C(C(=N)N)C=C3
• Target: PAI-1,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

25134287