UCB9608

SKU: orb1296276

Description

UCB9608 is a potent and selective oral inhibitor of PI4KIIIβ (IC50 = 11 nM), demonstrating high selectivity against related PI3KC2 isoforms. This tool compound is used in research to investigate phosphoinositide signaling in cellular models and has been evaluated in studies exploring its potential in vivo pharmacological effects.

Research Area

Signal Transduction

Key Properties

• CAS Number: 1616413-96-7
• MW: 410.47
• Purity: 99.96% (May vary between batches)
• Formula: C₂₀H₂₆N₈O₂
• SMILES: COc1ccc(NC(=O)N2CCN([C@@H](C)C2)c2nc(N)nc3n(C)ncc23)c(C)c1
• Target: PI4K
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.87 mM);DMSO:70 mg/mL (170.54 mM)

Bioactivity

• Target IC50:
  PI4KIIIβ:11 nM (cell free)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, Phosphatidylinositol 4 kinases, PI4 kinases, PI4K, PI4KIIIβ, UCB 9608, UCB9608, UCB-9608

Compound Identifiers

PubChem CID

76282073