UCB9386

SKU: orb2945908

Description

UCB9386 is a potent, brain-penetrant small molecule inhibitor selectively targeting Nuak1 (pIC50 10.1), with additional activity against Nuak2 and Kak2. This tool compound is used in vitro and in vivo to investigate the roles of AMPK-related kinases in neurological diseases and cancer biology.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 3096082-93-5
• MW: 478.548
• Formula: C₂₇H₂₆N₈O
• SMILES: C[C@H](C1=CC=CC=C1)N2C3=CC(=NC=C3N=C(C2=O)N4CC5(C4)CN(C5)C)C6=CN=C7N6N=CC=C7
• Target: AMPK,JAK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172676957