UC-764865

SKU: orb2279717

Description

UC-764865 (UC764865) is a small-molecule inhibitor that targeted ubiquitin-conjugating enzyme UBE2N active site.UC-764865 blocks ubiquitination of innate immune- and inflammatory-related substrates in human AML cell lines.Inhibition of UBE2N function disrupted oncogenic immune signaling by promoting cell death of leukemic HSPCs while sparing normal HSPCs in vitro.

Key Properties

• CAS Number: 2566480-63-3
• MW: 324.396842956543
• Purity: >98%
• Formula: C₁₈H₁₆N₂O₂S
• SMILES: C(C1=CC=C(OC)C=C1)(=O)/C=C\SC1NC2=CC(C)=CC=C2N=1

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

42555286