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UA2239

SKU: orb3174481

Description

UA2239 is an antimalarial agent that falls under the category of acyclic nucleoside phosphonates. It disrupts essential cGMP-dependent exocytosis pathways by reducing cGMP levels and specifically targets guanylyl cyclase α (guanylyl cyclase α). UA2239 exhibits a rapid and irreversible inhibitory effect on Plasmodium parasites.

Research Area

Cell Biology, Infectious Disease & Virology, Molecular Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2455422-89-4
MW347.18
FormulaC9H12N5Na2O5P
SMILESO=P([O-])([O-])C[C@H](O)CCN1C2=C(C(N=C(N2)N)=O)N=C1.[Na+].[Na+]
TargetNucleoside Antimetabolite/Analog,Guanylate cyclase,Parasite

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information