Tyrphostin AG 112

SKU: orb1685371

Description

Tyrphostin AG 112 is a selective EGFR tyrosine kinase inhibitor that blocks receptor autophosphorylation. This compound is a valuable research tool for studying EGFR signaling pathways in cancer biology, applicable in both in vitro cellular assays and in vivo model systems.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 144978-82-5
• MW: 236.23
• Purity: 99.14%
• Formula: C₁₃H₈N₄O
• SMILES: C(=C(C(=C(C#N)C#N)N)C#N)C1=CC=C(O)C=C1
• Target: EGFR
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.47 mM);DMSO:50 mg/mL (211.66 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Tyrphostin AG 112, Tyrphostin AG112, Tyrphostin AG-112, inhibit, Inhibitor, HER1, Epidermal growth factor receptor, ErbB-1, EGFR

Compound Identifiers

PubChem CID

2045