Type-II-IN-1

SKU: orb3174627

Description

Type-II-IN-1 (Compound 3) is a Type II spleen tyrosine kinase (Syk) inhibitor with an IC50 value of 2.1 nM. Type-II-IN-1 binds to the DFG-out conformation of Syk, and it may be applied in immunology studies, including research on asthma.

Key Properties

• CAS Number: 1419299-81-2
• MW: 529.52
• Formula: C₂₉H₂₂F₃N₅O₂
• SMILES: O=C(NC1=CC=C(C(=C1)C2=CC=3C=NC(=NC3N(C2=O)C)NC=4C=CC=CC4)C)C5=CC=CC(=C5)C(F)(F)F
• Target: Syk

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Syk