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TYM-3-98

SKU: orb3134238

Description

TYM-3-98 is a selective inhibitor of PI3Kδ with an IC50 of 7.1 nM. It inhibits the proliferation of B lymphoma cells by inducing apoptosis and suppressing the PI3K/AKT/mTOR signaling pathway. In mouse/rat models, TYM-3-98 displays favorable pharmacokinetic properties and antitumor activity without significant toxicity.

Images & Validation

Key Properties

CAS Number2820244-59-3
MW592.05
FormulaC28H23ClFN7O3S
SMILESO=S(=O)(C=1C=CC=C(C1)N2N=C(C=3C=CC(Cl)=CC32)C(N4N=C(C=5C=CC(OC)=C(F)C5)C=6C(=NC=NC64)N)C)C
TargetPI3K,Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information

TYM-3-98 (orb3134238)

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