Tyloxapol

SKU: orb1225511

Description

Tyloxapol is a non-ionic detergent often used as a surfactant.

Key Properties

• CAS Number: 25301-02-4
• MW: 137.18
• Purity: >98% (HPLC)
• Formula: C₇₀H₁₂₄O₁₃
• SMILES: NCCC1=CC=C(O)C=C1
• Target: NF-κB
• Solubility: DMSO: 10 mM

Bioactivity

• In Vivo:
  Animal model: Twenty-one adult male Wistar rats, aged 11–12 weeks weighing 180-200 g. Dosage: 50 mg/kg. Administration: Injected intraperitoneally, BW, every other day. Result: Caused a significant (P < 0.05) elevation in the levels of TBARS combined with an inhibition of the antioxidant enzymes (GPx, GST, CAT, SOD) in rat plasma, liver, and brain. Induced DNA fragmentation and inhibited the activities of acetylcholinesterase and mono aminoxidase in the brain.
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Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

NF-κB