TY-52156

SKU: orb1307641

Description

TY-52156 is a potent and selective antagonist of the S1P3 receptor, exhibiting a Ki value of 110 nM. This compound is a valuable research tool for investigating sphingosine-1-phosphate signaling in cardiovascular and inflammatory processes, applicable in both in vitro and in vivo experimental models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 934369-14-9
• MW: 364.27
• Purity: 99.91% (May vary between batches)
• Formula: C₁₈H₁₉Cl₂N₃O
• SMILES: CC(C)(C)C(=O)C(\NNc1ccc(Cl)cc1)=N\c1ccc(Cl)cc1
• Target: S1P Receptor,LPL Receptor
• Solubility: DMSO:100 mg/mL (274.52 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.98 mM)

Bioactivity

• Target IC50:
  S1P3:（ki）110 nM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Lysophospholipid Receptor, LPL Receptor, LPLReceptor, LPL, Inhibitor, S1P Receptor, S1PReceptor, S1P3, TY52156, TY-52156, TY 52156

Compound Identifiers

PubChem CID

16046248