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TX2-121-1

SKU: orb1699088

Description

TX2-121-1 is a small molecule that induces proteasomal degradation of HER3, thereby blocking its downstream signaling and suppressing tumor cell proliferation. It is a valuable research tool for investigating HER3 biology and evaluating targeted degradation strategies in both in vitro and in vivo cancer models.

Research Area

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number1603845-42-6
MW716.91
FormulaC42H52N8O3
SMILESC(C[C@H](C(NCCN1CCC(CC1)N2C=3C(C(=N2)C4=CC(NC(C=C)=O)=C(OC5=CC=CC=C5)C=C4)=C(N)N=CN3)=O)C)C67CC8CC(C6)CC(C7)C8
TargetPROTACs,Others,Akt,ERK,EGFR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information