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Catalog Number | orb1230505 |
---|---|
Category | Proteins |
Description | TWEAK Recombinant Protein |
Form/Appearance | Lyophilized |
Purity | Greater than 98% by SDS-PAGE gel and HPLC analyses. |
Target | TNFSF12 |
UniProt ID | O43508 |
Protein Sequence | MKGRKTRARR AIAAHYEVHP RPGQDGAQAG VDGTVSGWEE ARINSSSPLR YNRQIGEFIV TRAGLYYLYC QVHFDEGKAV YLKLDLLVDG VLALRCLEEF SATAASSLGP QLRLCQVSGL LALRPGSSLR IRTLPWAHLK AAPFLTYFGL FQVH |
Source | E. coli |
Biological Activity | Assay #1: The ED50 as determined by the dose-dependent stimulation of IL-8 production by human PBMC is less than 10 ng/mL.Assay #2: TWEAK weakly induces the death of HT29 cells when cultured in the presence of IFN-gamma. The ED50 for this effect is between 30-45 ng/mL. |
NCBI | NP_003800.1 |
Storage | The lyophilized TWEAK recombinant protein is stable for at least 2 years from date of receipt at -20˚°C. Reconstituted TWEAK is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚°C. As with any protein, exposing TWEAK recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature. |
Alternative names | APO3L, DR3LG, TWEAK, APO3L, UNQ181/PRO207, Tumor n Read more... |
Note | For research use only |
Expiration Date | 6 months from date of receipt. |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. | |
The protein has a predicted molecular mass of 43.3 kDa after removal of the signal peptide. | |
Mammalian |
ELISA, IHC, WB | |
Human | |
Monoclonal | |
Unconjugated |
Greater than 90% as determined by SDS-PAGE. | |
38.9 kDa | |
E.coli |
> 95% as determined by SDS-PAGE and HPLC. | |
5.6 kDa | |
E.Coli |
ELISA, FC | |
Human | |
Monoclonal | |
Unconjugated |