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Tubulysin A

SKU: orb1679051

Description

Tubulysin A is a potent myxobacterial-derived natural product that disrupts microtubule dynamics, leading to anti-mitotic and pro-apoptotic effects. Its robust in vitro anticancer and anti-angiogenic activity has prompted further investigation in preclinical in vivo models for oncology research.

Research Area

Infectious Disease & Virology, Signal Transduction

Images & Validation

Key Properties

CAS Number205304-86-5
MW844.07
FormulaC43H65N5O10S
SMILESN([C@H](C[C@@H](OC(C)=O)C1=NC(C(N[C@@H](CC2=CC=C(O)C=C2)C[C@@H](C(O)=O)C)=O)=CS1)C(C)C)(C([C@@H](NC(=O)[C@@H]3N(C)CCCC3)[C@H](CC)C)=O)COC(CC(C)C)=O
TargetAntibiotic,ADC Cytotoxin,Microtubule Associated

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Protocol Information

Tubulysin A (orb1679051)

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Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

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