Tubulin polymerization-IN-72

SKU: orb2945436

Description

Tubulin polymerization-IN-72 (Compound 4a4) is a potent colchicine-site microtubule inhibitor with sub-nanomolar IC50 values (0.4-2.7 nM). It blocks tubulin assembly, causing G2/M phase arrest and apoptosis in cancer cells, supporting its investigation in anticancer research both in vitro and in vivo.

Research Area

Cell Biology, Signal Transduction

Key Properties

• MW: 338.379
• Formula: C₁₉H₁₉FN₄O
• SMILES: CNC1=NC2=C(C=C(C=C2)F)C(=N1)N3CCCC4=C3C=CC(=C4)OC
• Target: Apoptosis,Microtubule Associated

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172675257