Tubulin polymerization-IN-70

SKU: orb2695296

Description

Tubulin polymerization-IN-70 (Q19) is a colchicine-site tubulin polymerization inhibitor with potent antiproliferative activity. It induces G2/M arrest, apoptosis, ROS elevation, and mitochondrial dysfunction in vitro, and demonstrates anti-angiogenic effects in cancer research models.

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research, Signal Transduction

Key Properties

• MW: 397.47
• Formula: C₂₅H₂₃N₃O₂
• SMILES: [C@@H](NC(=O)C=1N(CC)N=CC1)(C(NC2=C(F)C=C([C@@H](C(C(=O)N3C[C@@H](C)N(C)CC3)NC(C(F)C4CC4)=O)C)C=C2)=O)[C@]5(CC[C@H](C)CC5)[H]
• Target: Apoptosis,Reactive Oxygen Species,Microtubule Associated

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

156189059