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Tubulin polymerization-IN-67

SKU: orb2664301

Description

Tubulin polymerization-IN-67 is a colchicine-site microtubule polymerization inhibitor (IC50 = 2.92 µM) with broad anti-proliferative activity against cancer cell lines. It induces G2/M arrest, apoptosis, and inhibits cell migration and angiogenesis. The compound has also demonstrated in vivo antitumor efficacy in mouse models.

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research, Signal Transduction

Images & Validation

Key Properties

TargetApoptosis,Reactive Oxygen Species,Microtubule Associated

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information