Tubulin polymerization-IN-64

SKU: orb3134551

Description

Tubulin polymerization-IN-64 (Compound 8a) is a microtubule polymerization inhibitor that functions by occupying the colchicine binding site on tubulin, with an IC50 of 6.9 μM. This compound suppresses the proliferation of cancer cell lines A549, HeLa, HCT116, and HT-29, with IC50 values of 2.42, 10.33, 6.28, and 5.33 μM, respectively. Tubulin polymerization-IN-64 induces cell cycle arrest at the G2/M phase and triggers apoptosis in A549 cells.

Research Area

Cell Biology, Signal Transduction

Key Properties

• Formula: C₂₅H₂₅NO₆
• Target: Microtubule Associated,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Microtubule Associated,Apoptosis