Tubulin polymerization-IN-43

SKU: orb1819015

Description

Tubulin polymerization-IN-43 is a colchicine-site inhibitor that disrupts microtubule assembly, leading to G2/M phase arrest and apoptosis in leukemia cells. This small molecule is a valuable research tool for studying cytoskeleton dynamics and anticancer mechanisms in both cellular and preclinical models.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 2773345-90-5
• MW: 351.3
• Purity: 99.98% (May vary between batches)
• Formula: C₁₇H₁₃F₄N₃O
• SMILES: N(C)(C=1C2=C(N=C(C(F)(F)F)N1)C=CC(F)=C2)C3=CC=C(OC)C=C3
• Target: Apoptosis,Microtubule Associated
• Solubility: DMSO:50 mg/mL (142.33 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Tubulin polymerization-IN-43, TubulinpolymerizationIN43, Tubulin polymerization, Microtubule Associated, MicrotubuleAssociated, apoptosis

Compound Identifiers

PubChem CID

168510543