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Tubulin inhibitor 49

SKU: orb2945282

Description

Tubulin inhibitor 49 (Compound 18) is a small molecule that inhibits tubulin polymerization (IC50 = 48 µM), leading to microtubule disruption, G2/M phase cell cycle arrest, and cytotoxicity in HeLa cells (IC50 = 8.8 µM). It is a useful research tool for studying antimitotic mechanisms and cancer cell biology in vitro.

Research Area

Cell Biology, Pharmacology & Drug Discovery; Cell Biology, Signal Transduction

Images & Validation

Key Properties

CAS Number1023875-75-3
MW377.38
Purity99.15% (May vary between batches)
FormulaC18H14F3N3OS
SMILESO=C(NC=1C=CC(=CC1)C=2N=C(SC2)NC3=CC=CC(=C3)C(F)(F)F)C
TargetMicrotubule Associated,Cell Cycle Arrest

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 90.00
5 mg
$ 150.00
10 mg
$ 220.00
25 mg
$ 400.00
50 mg
$ 610.00
100 mg
$ 940.00
DispatchUsually dispatched within 5-10 working days
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