Tubulin inhibitor 49

SKU: orb2945282

Description

Tubulin inhibitor 49 (Compound 18) is a small molecule that inhibits tubulin polymerization (IC50 = 48 µM), leading to microtubule disruption, G2/M phase cell cycle arrest, and cytotoxicity in HeLa cells (IC50 = 8.8 µM). It is a useful research tool for studying antimitotic mechanisms and cancer cell biology in vitro.

Research Area

Pharmacology & Drug Discovery; Cell Biology

Key Properties

• CAS Number: 1023875-75-3
• MW: 377.383
• Purity: 99.15% (May vary between batches)
• Formula: C₁₈H₁₄F₃N₃OS
• SMILES: O=C(NC=1C=CC(=CC1)C=2N=C(SC2)NC3=CC=CC(=C3)C(F)(F)F)C
• Target: Microtubule Associated,Cell Cycle Arrest

Storage & Handling

• Storage: store at low temperature,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

4232041