Tubulin-IN-62

SKU: orb3174293

Description

Tubulin-IN-62 is a potent tubulin inhibitor targeting the colchicine binding site. It has an IC50 of 17.2 nM in SKOV3 cells and 19.3 nM in HCC827 cells. Tubulin-IN-62 inhibits microtubule polymerization, arrests the cell cycle at the G2/M phase, and induces apoptosis. In xenograft tumor models, it demonstrates significant antitumor efficacy with good tolerability. Tubulin-IN-62 is applicable for research on ovarian cancer and non-small cell lung cancer.

Research Area

Cell Biology, Metabolism Research, Signal Transduction

Key Properties

• Target: Phosphatase,Apoptosis,Microtubule Associated

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Phosphatase,Apoptosis,Microtubule Associated