TT-232 TFA(147159-51-1 free base)

SKU: orb1305622

Description

This small molecule induces a biphasic activation of phosphotyrosine phosphatase activity in the SW620 human colon carcinoma cell line. It is a research tool for studying phosphatase signaling dynamics in cancer biology, applicable in both in vitro and in vivo experimental models.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2703745-48-4
• MW: 1061.16
• Purity: 99.80% (May vary between batches)
• Formula: C₄₇H₅₉F₃N₁₀O₁₁S₂
• SMILES: C[C@H]([C@@H](C(N)=O)NC([C@@H]1CSSC[C@@H](C(N[C@H](C(N[C@@H](C(N[C@H](C(N1)=O)CCCCN)=O)Cc(c[nH]2)c3c2cccc3)=O)Cc4ccc(O)cc4)=O)NC([C@@H](Cc5ccccc5)N)=O)=O)O.C(=O)(C(F)(F)F)O
• Target: Others,Somatostatin,Apoptosis
• Solubility: DMSO:55 mg/mL (51.83 mM)

Bioactivity

• In Vitro:
  TT2-32 strongly stimulates PTPase activity in a biphasic manner in a SW620 human colon tumor cell line as an early step in its signal transduction process.TT2-32-induced activation of PTPases may be an important signaling pathway in the inhibition of cell proliferation in colon carcinomas.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

TT 232 TFA(147159 51 1 free base), TT-232 TFA, TT232 TFA(147159511 free base), 147159-51-1, 147159-51-1 free base

Compound Identifiers

PubChem CID

156599050