TS-24

SKU: orb2282953

Description

TS-24 is a CTSS (cathepsin S) protease inhibitor that induces BRCA1-dependent apoptosis. It has demonstrated radiosensitizing effects in triple-negative breast cancer (TNBC) cell studies and in vivo xenograft models, supporting its investigation as a potential therapeutic agent.

Research Area

Cell Biology, Protein Biochemistry

Key Properties

• CAS Number: 1563260-97-8
• MW: 301.34
• Purity: 99.58% (May vary between batches)
• Formula: C₂₀H₁₅NO₂
• SMILES: O=C(C=CC1=CN(C=2C=CC=CC12)C)C=3OC=4C=CC=CC4C3
• Target: Cysteine Protease,Protease,Apoptosis
• Solubility: DMSO:30 mg/mL (99.56 mM)

Bioactivity

• Target IC50:
  cathepsin S:4.3 μM
• In Vitro:
  In MDA-MB-231 cells, TS-24 (0-10 μM; 24 hours) can inhibit cell migration.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Apoptosis, Protease, TS 24, TS24

Compound Identifiers

PubChem CID

176418961