TRPV1-IN-3

SKU: orb2944896

Description

TRPV1-IN-3 (compound 14) is a potent TRPV1 inhibitor used in pulmonary fibrosis research. It exhibits antifibrotic effects in vitro (IC50 = 0.51 μM) by suppressing TGF-β/Smads and MAPK signaling. In vivo, it reduces lung collagen deposition, improves alveolar structure, and enhances survival in a Bleomycin-induced mouse model of idiopathic pulmonary fibrosis.

Research Area

Neuroscience

Key Properties

• CAS Number: 87657-67-8
• MW: 296.36
• Formula: C₁₉H₂₀O₃
• SMILES: C(=C/C(CCCCC1=CC=CC=C1)=O)\C2=CC(O)=C(O)C=C2
• Target: TRP/TRPV Channel

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

10063155