(Trp63,Trp64)​-​C3a(63-77)

SKU: orb2563822

Description

(Trp63, Trp64)-C3a(63-77) is a potent synthetic C3a receptor agonist. It stimulates calcium mobilization with high potency (EC50 values from 0.8 to 9.5 nM) in human neutrophils and transfected RBL-2H3 cells. This analog is a valuable tool for investigating C3aR signaling in immunological and inflammatory processes in vitro.

Research Area

Cell Biology, Immunology & Inflammation

Key Properties

• Target: Complement System
• CAS Number: 130154-64-2
• MW: 1820.15
• Formula: C₈₆H₁₃₄N₂₆O₁₈
• SMILES: C([C@H](NC([C@H](CC=1C=2C(NC1)=CC=CC2)N)=O)C(NCC(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=C(O)C=C3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)C)=O)CC(C)C)=O)=O)CC(C)C)=O)CCCCN)=O)CO)=O)C)=O)CCCNC(=N)N)=O)=O)CCCCN)=O)CCCCN)=O)=O)C=4C=5C(NC4)=CC=CC5

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

49799079