TRK/ALK-IN-1

SKU: orb1744558

Description

TRK/ALK-IN-1 is a potent, dual-specificity inhibitor targeting TRKA (IC50=2.2 nM) and both wild-type and L1196M-mutant ALK. Its strong correlation between enzymatic and cellular anti-proliferative activity makes it a valuable chemical probe for oncology research, supporting investigations into TRK and ALK-driven cancers in vitro.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• MW: 657.18
• Formula: C₃₁H₃₅ClF₂N₈O₂S
• SMILES: CN1CCN(CC1)C2=C(C=C(C=C2)NC(=O)[C@@H]3CCCN3C4=NC(=NC=C4Cl)NC5=CC(=CC(=C5)F)F)C(=O)N6CCSCC6
• Target: Trk receptor,Others,ALK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

163409046