TrkA-IN-1

SKU: orb1708325

Description

TrkA-IN-1 is a potent, cell-active, and selective inhibitor of Tropomyosin-related kinase A (TrkA), demonstrating an IC50 of 99 nM. This compound serves as a valuable research tool for investigating TrkA signaling in pain pathways and has shown analgesic efficacy in preclinical in vivo models.

Research Area

Signal Transduction

Key Properties

• CAS Number: 1680179-43-4
• MW: 392.45
• Formula: C₂₅H₂₀N₄O
• SMILES: Cc1ncc(NC(=O)NC2c3ccccc3-c3ccccc23)c(n1)-c1ccccc1
• Target: Trk receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

117967296