TRK-IN-30

SKU: orb2945396

Description

TRK-IN-30 (Compound C11) is a potent pan-TRK inhibitor effective against TRKA, TRKB, TRKC, and the TRKAG595R mutant. It blocks downstream PI3K/AKT and MEK/ERK signaling, leading to suppressed proliferation, cell cycle arrest, and apoptosis in cancer cells like Km-12, making it a valuable tool for oncology research in vitro.

Research Area

Cell Biology, Signal Transduction

Key Properties

• MW: 427.455
• Formula: C₂₄H₂₁N₅O₃
• SMILES: COC1=C(C=C(C=C1)NC(=O)C2=C(C(=CC=C2)NC3=CC4=C(C=C3)C(=CN4)C#N)N)OC
• Target: PI3K,Trk receptor,ERK,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172676868