TRK II-IN-1

SKU: orb1744485

Description

TRK II-IN-1 is a potent type II pan-TRK inhibitor with additional activity against FLT3 and RET. It is a valuable chemical probe for investigating TRK-driven oncogenesis in both cellular and animal models, aiding in the study of resistance mechanisms and targeted therapy development.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Key Properties

• CAS Number: 2904690-41-9
• MW: 564.6
• Formula: C₂₉H₃₁F₃N₈O
• SMILES: CN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)[C@@H]3CCN(C3)C4=NN5C(=NC=C5C6=CC=CC=N6)C=C4)C(F)(F)F
• Target: c-RET,Trk receptor,VEGFR,FLT

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

165177995