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Tris(4-aminophenyl)methane

SKU: orb1217893

Description

Tris(4-aminophenyl)methane, a triphenylmethane dye, is a weak HCV helicase inhibitor.

Research Area

Signal Transduction

Images & Validation

Key Properties

CAS Number548-61-8
MW289.37
Purity>98% (HPLC)
FormulaC19H19N3
SMILESNc1ccc(C(c(cc2)ccc2N)c(cc2)ccc2N)cc1
TargetHCV
SolubilityIn Vitro: DMSO : 50 mg/mL (172.79 mM)

Bioactivity

In Vitro
Tris(4-aminophenyl)methane (Compound 8) shows weak HCV helicase inhibition (30% inhibition at 100 μM). To preserve RNA in a biological sample for analysis, the sample is incubated with an RNA preservative capable of precipitating RNA in an aqueous solution, such as a triphenylmethane dye (e. g., methyl green, crystal violet, pararosaniline, or Tris(4-aminophenyl)methane), cresyl violet, or cobalt ions. RNA preservation may be used in an immunostaining assay and other histochemical methods.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Leucopararosaniline

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Protocol Information