Trilaciclib hydrochloride

SKU: orb1219373

Description

Trilaciclib hydrochloride is an inhibitor of CDK4/6 (IC50s: 1 nM and 4 nM for CDK4 and CDK6).Incubation with Trilaciclib hydrochloride (G1T28) for 24 hours can induce a strong G1 cell cycle arrest (time=0). Cells have re-entered the cell cycle and demonstrate cell-cycle kinetics similar to untreated control cells By 16 hours after Trilaciclib hydrochloride washout.

Images & Validation

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Key Properties

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CAS Number	1977495-97-8
MW	519.5
Purity	>98% (HPLC)
Formula	C₂₄H₃₂Cl₂N₈O
Target	Cdk4/cyclin D1\|cdk6/cyclin D3

Storage & Handling

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Storage	Storage temperature: -20°C. Stability: ≥ 2 years
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

Cdk4/cyclin D1|cdk6/cyclin D3

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