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Catalog Number | orb1741445 |
---|---|
Category | Small Molecules |
Description | Trifluoromethyl-tubercidin |
CAS Number | 1854086-05-7 |
Purity | 0.999 |
MW | 334.25 |
SMILES | O[C@H]1[C@H](N2C=3C(C(C(F)(F)F)=C2)=C(N)N=CN3)O[C@H](CO)[C@H]1O |
Formula | C12H13F3N4O4 |
Biological Activity | Trifluoromethyl-tubercidin (TFMT) inhibits host MTr1 and suppresses virus replication. TFMT inhibits MTr1 through interaction at its S-adenosyl-l-methionine binding pocket to restrict influenza virus replication. TFMT was effective in inhibiting viral replication in mice, displayed little toxicity. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |