Triclabendazole sulfoxide

SKU: orb1303678

Description

Triclabendazole sulfoxide (TCBZ-SO), the primary active plasma metabolite of Triclabendazole, acts as an inhibitor of the ABCG2/BCRP membrane transporter. This small molecule is utilized in parasitology research for its anthelmintic properties, supporting in vitro and in vivo studies against trematode infections.

Research Area

Infectious Disease & Virology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 100648-13-3
• MW: 375.66
• Formula: C₁₄H₉Cl₃N₂O₂S
• SMILES: CS(=O)c1nc2cc(Oc3cccc(Cl)c3Cl)c(Cl)cc2[nH]1
• Target: BCRP|||Parasite
• Solubility: DMSO:70 mg/mL (186.34 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

TCBZ-SO, Triclabendazole sulfoxide, Breast cancer resistance protein, ABCG2, BCRP, Parasite, inhibit, Inhibitor

Compound Identifiers

PubChem CID

127657