Triciribine phosphate

SKU: orb1706005

Description

Triciribine phosphate (VD 002) is a potent and selective AKT inhibitor that triggers caspase-dependent apoptosis and cell cycle arrest, suppressing angiogenesis. It is widely applied in leukemia research, demonstrating efficacy in both in vitro cellular assays and in vivo xenograft models.

Research Area

Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 61966-08-3
• MW: 400.28
• Purity: 99.43% (May vary between batches)
• Formula: C₁₃H₁₇N₆O₇P
• SMILES: NC=1C=2C=3C(N(C2)[C@@H]4O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]4O)=NC=NC3N(C)N1
• Target: Apoptosis,Akt,ATPase
• Solubility: H2O:5 mg/mL (12.49 mM);DMSO:8.06 mg/mL (20.14 mM)

Storage & Handling

• Storage: keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Akt, Apoptosis, PTX200, PTX-200, PTX 200, VD 002, TCN-P, VQD 002, VQD002, VQD-002

Compound Identifiers

PubChem CID

43860