Trichodermamide B

SKU: orb2646100

Description

Trichodermamide B is a potent small molecule JAK/STAT3 pathway inhibitor with an IC50 of 0.12 µM against HCT116 colon cancer cells. It demonstrates significant antiproliferative and pro-apoptotic activity in vitro, supporting its investigation as a potential chemotherapeutic agent in oncology research.

Research Area

Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 508218-12-0
• MW: 450.83
• Formula: C₂₀H₁₉ClN₂O₈
• SMILES: O(C)C1=C2C(C=C(NC(=O)C=3C[C@@]4(O)[C@@](ON3)([C@H](O)C=C[C@H]4Cl)[H])C(=O)O2)=CC=C1OC
• Target: STAT,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

639644