TREX1-IN-3

SKU: orb2944843

Description

TREX1-IN-3 (Compound 95) is a potent small molecule inhibitor of the TREX1 and TREX2 exonucleases, demonstrating sub-micromolar cellular activity in HCT116 cells. This compound is a valuable research tool for investigating the role of these nucleases in oncology, supporting both in vitro and in vivo cancer-related studies.

Research Area

Cell Biology, Molecular Biology

Key Properties

• CAS Number: 2588445-13-8
• MW: 490.898
• Formula: C₂₄H₁₉ClN₆O₄
• SMILES: [C@@H](N(C)C1=NC(C(NC=2C=NOC2)=O)=C(O)C(=O)N1C)(C3=CC(C#N)=CC=C3)C4=C(Cl)C=CC=C4
• Target: DNA/RNA Synthesis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172677322