Transketolase-IN-4

SKU: orb1744816

Description

Transketolase-IN-4 is a small molecule inhibitor of transketolase (IC50 = 3.9 μM) and Mycobacterium tuberculosis DXS (IC50 = 114.1 μM). It demonstrates anti-proliferative activity against SW620, LS174T, and MIA PaCa-2 cancer cell lines in vitro, making it a useful research tool for studying metabolic pathways in oncology and infectious disease.

Research Area

Infectious Disease & Virology, Metabolism Research

Key Properties

• CAS Number: 419547-73-2
• MW: 335.79
• Purity: 99.52% (May vary between batches)
• Formula: C₁₉H₁₄ClN₃O
• SMILES: O=C1N2C(=C(C=N2)C3=CC=C(Cl)C=C3)NC(CC4=CC=CC=C4)=C1
• Target: Antibacterial,Transketolase
• Solubility: DMSO:112.5 mg/mL (335.03 mM)

Bioactivity

• Target IC50:
  Transketolase:3.9 μM|Mycobacterium tuberculosis DXS:14.1 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Mycobacterium tuberculosis, Bacterial

Compound Identifiers

PubChem CID

1281059