trans-VH 101-Thiol-C-cyclohexane-p-C-OTs

SKU: orb2945094

Description

This compound is a VHL E3 ligase ligand-linker conjugate, specifically designed for synthesizing the PROTAC degrader dBAZ2. It serves as a key intermediate in chemical biology research for constructing heterobifunctional degraders, enabling target validation studies in both cellular and biochemical assays.

Research Area

Pharmacology & Drug Discovery

Key Properties

• MW: 815.049
• Formula: C₄₀H₅₁FN₄O₇S₃
• SMILES: CC1=CC=C(C=C1)S(=O)(=O)OCC2CCC(CC2)CSC(C)(C)[C@@H](C(=O)N3C[C@@H](C[C@H]3C(=O)NCC4=CC=C(C=C4)C5=C(N=CS5)C)O)NC(=O)C6(CC6)F
• Target: E3 Ligase Ligand-Linker Conjugates

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172676832